Trio Smart Breath Test for SIBO

A smarter, more complete way to uncover the root of your digestive issues.

Digestive discomfort is one of the most common health complaints—and for many, the underlying cause is Small Intestinal Bacterial Overgrowth (SIBO). SIBO occurs when bacteria that normally live in the large intestine migrate to the small intestine, where they ferment food prematurely. This process produces excess gases that lead to bloating, abdominal pain, gas, diarrhea, constipation, and nutrient malabsorption.

The Trio Smart Breath Test by Gemelli Biotech is a state-of-the-art, non-invasive diagnostic tool designed to detect these bacterial gases in exhaled breath. Unlike traditional breath tests, Trio Smart measures hydrogen, methane, and hydrogen sulfide, providing the most complete picture of microbial activity in the small intestine.

This advanced test represents the next generation of SIBO diagnostics, offering greater accuracy, more actionable insights, and improved guidance for treatment.

Learn how it fits into our broader Advanced Testing panel.

Why Trio Smart Is Different

Conventional breath tests typically measure only hydrogen and methane gases. However, research shows that hydrogen sulfide-producing bacteria can also contribute to SIBO—and without measuring this gas, many cases go undetected.

The Trio Smart test is the first and only FDA-cleared breath test that includes hydrogen sulfide in addition to hydrogen and methane. This innovation allows for:

• More accurate detection of SIBO subtypes

• A comprehensive view of how bacterial fermentation is impacting your gut

• Better-informed decisions about targeted treatment strategies

By capturing all three key gases, Trio Smart eliminates the blind spots of older breath tests and provides clear, quantitative measurements of what’s truly happening in your small intestine.

Who Should Consider the Trio Smart Breath Test?

This test is ideal for anyone who is struggling with persistent digestive symptoms that haven’t improved with general approaches. It’s especially valuable for individuals experiencing:

• Bloating or abdominal distension after meals

• Excessive gas, discomfort, or pressure in the digestive tract

• Diarrhea, constipation, or alternating bowel habits

• Abdominal pain or cramping linked to eating

• Symptoms of Irritable Bowel Syndrome (IBS) that remain unresolved

It’s also recommended for people with higher risk factors for SIBO, including:

• A history of food poisoning or gastroenteritis

• Frequent antibiotic use, which disrupts the balance of gut bacteria

• Prior gastrointestinal surgery or structural abnormalities

• Conditions like hypothyroidism or diabetes, which can slow gut motility

If you suspect SIBO or have been diagnosed with IBS but still lack clear answers, the Trio Smart Breath Test can help pinpoint the true cause of your symptoms.

If you're grappling with persistent bloating, gas, constipation, or diarrhea—not resolved by typical protocols—Trio‑Smart offers precise diagnostics. Following your results, our Gut Health & Nutrient Optimization Program provides data-driven, tailored treatment plans.

Why Accurate SIBO Detection Matters

SIBO can lead to more than just discomfort. Left unaddressed, it can contribute to:

• Nutrient deficiencies, especially vitamins B12, A, D, E, and K

• Intestinal inflammation and leaky gut, worsening food sensitivities

• Metabolic imbalances that affect your overall energy and well-being

By identifying the exact gas patterns causing your symptoms, you and your provider can create a targeted treatment plan—whether that involves antibiotics, herbal antimicrobials, dietary changes, or probiotic strategies designed specifically for your type of SIBO.

Benefits of the Trio Smart Breath Test

• Comprehensive Analysis: Measures hydrogen, methane, and hydrogen sulfide gases for the most complete SIBO assessment.

• Quantitative Results: Provides clear data to guide personalized treatment plans.

• Improved Accuracy: Detects SIBO subtypes that conventional tests can miss.

• Actionable Insights: Helps resolve stubborn digestive symptoms, support gut healing, and improve nutrient absorption.

With these insights, you’ll no longer be guessing about the root cause of your gut issues—you’ll have real answers and a clear path forward.

Because Trio‑Smart measures all three primary gases (H₂, CH₄, H₂S), it uncovers types of overgrowth that other breath tests miss—leading to faster, targeted resolution. Talk with our experts to interpret your results through our Consultation Services.